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Identification of CD38 high Monocyte as a Candidate Diagnostic Biomarker and Therapeutic Target for Sepsis

27 Mar 2025

Abstract excerpt

Abstract Sepsis is characterized by a systemic host response to infection. Monocytes, as major mediators of acute infection, are implicated in complications among critically ill patients. Identifying key monocyte subsets and their activation states is essential for diagnosis and delineating new therapeutic targets for sepsis. Here, single cell transcriptome sequencing and mass cytometry are used to assess...

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PMID: 40145840
DOI: 10.1002/advs.202500457

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