Article
Genetic variants of PON1, GSTM1, GSTT1, and locus 9p21.3, and the risk for premature coronary artery disease in Yucatan, Mexico.
American journal of human biology : the official journal of the Human Biology Council - 1 May 2022
García-González Igrid, Pérez-Mendoza Gerardo, Solís-Cárdenas Alberto, Flores-Ocampo Jorge, Herrera-Sánchez Luis Fernando, Mendoza-Alcocer Renan, González-Herrera Lizbeth
Abstract excerpt
OBJECTIVE: Genetic variants of PON1, rs70587, rs662, rs854560, GSTM1, and GSTT1 and two single nucleotide polymorphisms (SNP) at 9p21.3 locus, rs1333049, and rs2383207; were evaluated in association with the risk for premature coronary artery disease (CAD) in a population of Yucatan, Mexico. These genes are involved in the inactivation of pro-oxidants and pro-inflammatory mediators, lipid and xenobiotic...
