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Article

Epistasis analysis of metabolic genes polymorphisms associated with ischemic heart disease in Yucatan.

Clinica e investigacion en arteriosclerosis : publicacion oficial de la Sociedad Espanola de Arteriosclerosis - 1 Jan 2000

García-González Igrid, López-Díaz Roger Iván, Canché-Pech José Reyes, Solís-Cárdenas Alberto de Jesús, Flores-Ocampo Jorge A, Mendoza-Alcocer Renán, Herrera-Sánchez Luis Fernando, Jiménez-Rico Marco Antonio, Ceballos-López Adrián Alejandro, López-Novelo María E

Abstract excerpt

OBJECTIVE: Epistasis is a type of genetic interaction that could explain much of the phenotypic variability of complex diseases. In this work, the effect of epistasis of metabolic genes and cardiovascular risk on the susceptibility to the development of ischemic heart disease in Yucatan was determined. METHODS: Case-control study in 79 Yucatecan patients with ischemic heart disease and 101 healthy controls...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29395491
DOI: 10.1016/j.arteri.2017.11.002

Genes

GSTT1
MTHFR
PON1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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