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Article

Novel biallelic DNHD1 variants associated with male infertility with severe MMAF phenotype.

Asian journal of andrology - 1 Mar 2026

Uddin Islam, Zafar Iqra, Xu Cao-Ling, Xing Xue-Mei, Li Wen-Qing, Zou Jia-Qi, Tahmasebi Hossein, Khan Muhammad Imran, Wu Li-Min, Bao Jian-Qiang

Abstract excerpt

Multiple morphological abnormalities of the sperm flagella (MMAF), characterized by severe morphological sperm defects, such as absent, short, irregular caliber, and coiled flagella with extreme asthenoteratozoospermia, are the most prevalent cause of human male infertility. Previous studies have identified several genes linked to MMAF; however, the increasing incidence of infertility indicates that most affected...

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Identifiers

PMID: 41214471
DOI: 10.4103/aja202535
PMCID: PMC13065322

Genes

DNHD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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