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Ubiquitin-specific peptidase 37: an important cog in the oncogenic machinery of cancerous cells

10 Nov 2021

Abstract excerpt

Protein ubiquitination is one of the most crucial posttranslational modifications responsible for regulating the stability and activity of proteins involved in homeostatic cellular function. Inconsistencies in the ubiquitination process may lead to tumorigenesis. Ubiquitin-specific peptidases are attractive therapeutic targets in different cancers and are being evaluated for clinical development....

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PMID: 34758854
DOI: 10.1186/s13046-021-02163-7

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