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Targeting ubiquitin specific protease 7 in cancer: A deubiquitinase with great prospects

20 May 2018

Abstract excerpt

Deubiquitinase (DUB)-mediated cleavage of ubiquitin chain balances ubiquitination and deubiquitination for determining protein fate. USP7 is one of the best characterized DUBs and functionally important. Numerous proteins have been identified as potential substrates and binding partners of USP7; those play crucial roles in diverse array of cellular and biological processes including tumour suppression, cell...

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PMID: 29781103
DOI: 10.1002/cbf.3336

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