Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of ubiquitin-specific peptidases in cancer progression

27 May 2019

Abstract excerpt

Protein ubiquitination is an important mechanism for regulating the activity and levels of proteins under physiological conditions. Loss of regulation by protein ubiquitination leads to various diseases, such as cancer. Two types of enzymes, namely, E1/E2/E3 ligases and deubiquitinases, are responsible for controlling protein ubiquitination. The ubiquitin-specific peptidases (USPs) are the main members of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glycosylation and Glycoproteins Research
Share to Peptidase Inhibition and Analysis
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31133011
DOI: 10.1186/s12929-019-0522-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of ubiquitin-specific peptidases in cancer progressionPMID 31133011Read ↗

The role of ubiquitin-specific peptidases in glioma progressionSemantic proximity Read ↗

Ubiquitin-Specific Peptidase 7: A Novel Deubiquitinase That Regulates Protein Homeostasis and CancersSemantic proximity Read ↗

Emerging Potential of Therapeutic Targeting of Ubiquitin-Specific Proteases in the Treatment of CancerSemantic proximity Read ↗

Emerging potential of ubiquitin-specific proteases and ubiquitin-specific proteases inhibitors in breast cancer treatmentSemantic proximity Read ↗

Ubiquitin-specific peptidase 10, a deubiquitinating enzyme: Assessing its role in tumor prognosis and immune responseSemantic proximity Read ↗

Targeting deubiquitinase USP28 for cancer therapySemantic proximity Read ↗

Spotlights on ubiquitin-specific protease 12 (USP12) in diseases: from multifaceted roles to pathophysiological mechanismsSemantic proximity Read ↗

Ubiquitin-specific protease 28: the decipherment of its dual roles in cancer developmentSemantic proximity Read ↗

Deubiquitylating Enzymes in Cancer and ImmunitySemantic proximity Read ↗

Advances in Deubiquitinating Enzyme Inhibition and Applications in Cancer TherapeuticsSemantic proximity Read ↗

The role of the ubiquitin-proteasome pathway in cancer development and treatmentSemantic proximity Read ↗

Deubiquitinases in Cancers: Aspects of Proliferation, Metastasis, and ApoptosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.