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Emerging Role of Ubiquitin-Specific Protease 19 in Oncogenesis and Cancer Development

12 May 2022

Abstract excerpt

Ubiquitination and ubiquitin-like post-translational modifications control the activity and stability of different tumor suppressors and oncoproteins. Hence, regulation of this enzymatic cascade offers an appealing scenario for novel antineoplastic targets discovery. Among the different families of enzymes that participate in the conjugation of Ubiquitin, deubiquitinating enzymes (DUBs), responsible for removing...

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PMID: 35646888
DOI: 10.3389/fcell.2022.889166

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