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Article

A Swedish Haplotype GWAS in Familial and Sporadic Site-Specific Colorectal Cancer.

International journal of molecular sciences - 18 Mar 2026

Vermani Litika, Barot Shabane, Lindblom Annika

Abstract excerpt

Genetic variants specific to anatomical subsites of colorectal cancer are known to play a crucial role in its prognosis and treatment. We undertook a haplotype-based genome-wide association study (GWAS) to identify specific genetic risk loci for three sites: cecum, right colorectum, and left colorectum. Six different haplotype GWAS were performed using familial and sporadic colorectal cancer cases with tumors at...

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Case-Control Studies
Colorectal Neoplasms
Genetic Predisposition to Disease
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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PMID: 41898618
DOI: 10.3390/ijms27062758
PMCID: PMC13026190

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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