Article
The heterogeneity of cancer endothelium: The relevance of angiogenesis and endothelial progenitor cells in cancer microenvironment.
Microvascular research - 1 Nov 2021
Armani Giovanna, Pozzi Emma, Pagani Anna, Porta Camillo, Rizzo Mimma, Cicognini Daniela, Rovati Bianca, Moccia Francesco, Pedrazzoli Paolo, Ferraris Elisa
Abstract excerpt
Tumor-associated vessels constitution is the result of angiogenesis, the hallmark of cancer essential for tumor to develop in dimension and to spread throughout the organism. Tumor endothelium is configured as an active functioning organ capable of determine interaction with the immune response and all the other components of the variegate cancer microenvironment, determining reciprocal influence. Angiogenesis is...
Topics
- Angiogenesis Inhibitors
- Angiogenic Proteins
- Animals
- Cell Lineage
- Endothelial Progenitor Cells
- Gene Expression Regulation, Neoplastic
- Humans
- Neoplasms
- Neovascularization, Pathologic
- Phenotype
- Signal Transduction
- Tumor Microenvironment