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Endothelial cell differentiation of human breast tumour stem/progenitor cells

10 Apr 2008

Abstract excerpt

Breast tumour stem cells have been reported to differentiate in the epithelial lineage but a cross-lineage potential has not been investigated. We aimed to evaluate whether breast tumour stem cells were able to differentiate also into the endothelial lineage. We isolated and cloned a population of breast tumour stem cells, cultured as mammospheres that expressed the stem markers nestin and Oct-4 and not...

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PMID: 18410528
DOI: 10.1111/j.1582-4934.2008.00338.x

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