Article
Pathophysiology, genetic, and therapy of arterial stiffness.
Bio-medical materials and engineering - 1 Jan 2006
Cattan Valérie, Kakou Augustine, Louis Huguette, Lacolley Patrick
Abstract excerpt
Stiffening of large arteries is considered as an independent predictor of cardiovascular events. This article summarizes recent theories on the mechanisms contributing to arterial stiffness involving extracellular matrix proteins, endothelial and smooth muscle cells, cell-matrix interactions, and genetic background. Despite the important role of genetic factors in essential hypertension, little is known about the...
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