Article
Chromosomal mapping of quantitative trait loci controlling elastin content in rat aorta.
Hypertension (Dallas, Tex. : 1979) - 1 Mar 2005
Gauguier Dominique, Behmoaras Jacques, Argoud Karène, Wilder Steven P, Pradines Christelle, Bihoreau Marie Thérèse, Osborne-Pellegrin Mary, Jacob Marie Paule
Abstract excerpt
Extracellular matrix molecules such as elastin and collagens provide mechanical support to the vessel wall. In addition to its structural role, elastin is a regulator that maintains homeostasis through biologic signaling. Genetically determined minor modifications in elastin and collagen in the aorta could influence the onset and evolution of arterial pathology, such as hypertension and its complications. We...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.