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Article

Frequent HRAS Mutations in Malignant Ectomesenchymoma

12 Feb 2016

Abstract excerpt

Malignant ectomesenchymoma (MEM) is an exceedingly rare pediatric sarcoma with a predilection for infants and young children and is composed of dual malignant mesenchymal and neuroectodermal components. Microscopically, MEM displays areas of rhabdomyosarcoma (RMS) with intermixed neuronal/neuroblastic foci. The molecular alterations associated with MEM and its relationship with embryonal RMS (ERMS) and malignant...

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PMID: 26872011
DOI: 10.1097/pas.0000000000000612

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