Article
Single nucleotide polymorphisms within HLA region are associated with the outcomes of unrelated cord blood transplantation.
Scientific reports - 9 Nov 2021
Chen Ding-Ping, Chang Su-Wei, Jaing Tang-Her, Wang Wei-Ting, Hsu Fang-Ping, Tseng Ching-Ping
Abstract excerpt
Cord blood transplantation (CBT) provides a treatment scheme for hematologic diseases and leukemia in both children and adults. However, adverse reactions and transplantation-related death may still occur in patients receiving CBT even when donor and recipient have fully matched HLA in high-resolution HLA typing analysis. Single nucleotide polymorphisms (SNPs) of HLA-related and unrelated genes are known to...
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