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HIST1H1B Promotes Basal-Like Breast Cancer Progression by Modulating CSF2 Expression

22 Oct 2021

Abstract excerpt

BACKGROUND: Basal-like breast cancer (BLBC) is associated with a poor clinical outcome; however, the mechanism of BLBC aggressiveness is still unclear. It has been shown that a linker histone functions as either a positive or negative regulator of gene expression in tumors. Here, we aimed to investigate the possible involvement and mechanism of HIST1H1B in BLBC progression. EXPERIMENTAL DESIGN: We analyzed...

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PMID: 34746019
DOI: 10.3389/fonc.2021.780094

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