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Regulation of signal transduction pathways in colorectal cancer: implications for therapeutic resistance

22 Oct 2021

Abstract excerpt

Resistance to anti-cancer treatments is a critical and widespread health issue that has brought serious impacts on lives, the economy and public policies. Mounting research has suggested that a selected spectrum of patients with advanced colorectal cancer (CRC) tend to respond poorly to both chemotherapeutic and targeted therapeutic regimens. Drug resistance in tumours can occur in an intrinsic or acquired...

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PMID: 34733591
DOI: 10.7717/peerj.12338

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