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Article

The Role of ATP-Binding Cassette Subfamily A in Colorectal Cancer Progression and Resistance

10 Jan 2023

Abstract excerpt

Colorectal cancer (CRC) is one of the most common malignancies worldwide; it is the fourth leading cause of cancer-related deaths. CRC arises due to mutations that can affect oncogenes, tumour suppressor genes and DNA repair genes. The lack of novel diagnostic and therapeutic targets and the development of chemoresistance are some of the major issues when dealing with CRC. The overexpression of ATP-binding...

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PMID: 36674859
DOI: 10.3390/ijms24021344

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