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Signaling pathways involved in colorectal cancer: pathogenesis and targeted therapy

6 Oct 2024

Abstract excerpt

Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality worldwide. Its complexity is influenced by various signal transduction networks that govern cellular proliferation, survival, differentiation, and apoptosis. The pathogenesis of CRC is a testament to the dysregulation of these signaling cascades, which culminates in the malignant transformation of colonic epithelium. This review...

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PMID: 39370455
DOI: 10.1038/s41392-024-01953-7

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