Article
Acute Promyelocytic Leukemia with a BCR-ABL1 Rearrangement in a Minor Clone.
Laboratory medicine - 5 May 2022
Cho Yonggeun, Hyun Jungwon, Kim Miyoung, Han Boram, Lee Young Kyung
Abstract excerpt
Acute promyelocytic leukemia (APL) is a type of acute myeloid leukemia characterized by predominating abnormal promyelocytes with a PML-RARA rearrangement or a variant thereof. BCR-ABL1 rearrangement is an oncogenic event that is usually associated with chronic myeloid leukemia but also occurs in both acute lymphoblastic and acute myeloid leukemias and in healthy individuals. However, APL with concurrent PML-RARA...
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