Article
Genetic risk scores for major psychiatric disorders and the risk of postpartum psychiatric disorders.
Translational psychiatry - 11 Nov 2019
Bauer Anna E, Liu Xiaoqin, Byrne Enda M, Sullivan Patrick F, Wray Naomi R, Agerbo Esben, Nyegaard Mette, Grove Jakob, Musliner Katherine L, Ingstrup Katja G, Johannsen Benedicte M W, Mægbæk Merete L, Wang Yunpeng, Nordentoft Merete, Mors Ole, Børglum Anders D, Werge Thomas, Hougaard David M, Mortensen Preben Bo, Munk-Olsen Trine, Meltzer-Brody Samantha
Abstract excerpt
Postpartum psychiatric disorders are heritable, but how genetic liability varies by other significant risk factors is unknown. We aimed to (1) estimate associations of genetic risk scores (GRS) for major depression (MD), bipolar disorder (BD), and schizophrenia (SCZ) with postpartum psychiatric disorders, (2) examine differences by prior psychiatric history, and (3) compare genetic and familial risk of postpartum...
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