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Article

Association of Inherited Mutations in DNA Repair Genes with Localized Prostate Cancer.

European urology - 1 Jun 2022

Lee Daniel J, Hausler Ryan, Le Anh N, Kelly Gregory, Powers Jacquelyn, Ding James, Feld Emily, Desai Heena, Morrison Casey, Doucette Abigail, Gabriel Peter, Genetics Center Regeneron, Judy Renae L, Weaver Joellen, Kember Rachel, Damrauer Scott M, Rader Daniel J, Domchek Susan M, Narayan Vivek, Schwartz Lauren E, Maxwell Kara N

Abstract excerpt

BACKGROUND: Identification of germline mutations in DNA repair genes has significant implications for the personalized treatment of individuals with prostate cancer (PrCa). OBJECTIVE: To determine DNA repair genes associated with localized PrCa in a diverse academic biobank and to determine genetic testing burden. DESIGN, SETTING, AND PARTICIPANTS: A cross-sectional study of 2391 localized PrCa patients was...

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Identifiers

PMID: 34711450
DOI: 10.1016/j.eururo.2021.09.029
PMCID: PMC9035481

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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