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Association of the Level of Neurofilament Light With Disease Severity in Patients With Spinocerebellar Ataxia Type 2

27 Oct 2021

Abstract excerpt

Background and Objectives Few biochemical markers have been identified in spinocerebellar ataxia type 2 (SCA2). This study aimed to determine the levels of neurofilament light (NfL) in patients with SCA2 and to identify whether they are associated with disease severity. Methods Participants were recruited from 1 medical center in China, and individuals with SCA2 were genetically diagnosed. NfL levels were...

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PMID: 34706976
DOI: 10.1212/wnl.0000000000012945

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