Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of neurofilament aggregation in neurodegeneration: lessons from rare inherited neurological disorders

16 May 2019

Abstract excerpt

Many neurodegenerative disorders, including Parkinson's, Alzheimer's, and amyotrophic lateral sclerosis, are well known to involve the accumulation of disease-specific proteins. Less well known are the accumulations of another set of proteins, neuronal intermediate filaments (NFs), which have been observed in these diseases for decades. NFs belong to the family of cytoskeletal intermediate filament proteins (IFs)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyotrophic Lateral Sclerosis Research
Share to Neurogenetic and Muscular Disorders Research
Share to Skin and Cellular Biology Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31097008
DOI: 10.1186/s13024-019-0318-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 18 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of neurofilament aggregation in neurodegeneration: lessons from rare inherited neurological disordersPMID 31097008Read ↗

Neurofilaments and neurological disease.Semantic proximity Read ↗

Neurofilaments: Novel findings and future challengesSemantic proximity Read ↗

Neurofilamentopathy in Neurodegenerative DiseasesSemantic proximity Read ↗

The dazzling rise of neurofilaments: Physiological functions and roles as biomarkers.Semantic proximity Read ↗

Neurofilament proteins in neurodegenerative diseasesSemantic proximity Read ↗

Neuronal intermediate filaments and ALS: A new look at an old questionSemantic proximity Read ↗

Neurofilament Biophysics: From Structure to BiomechanicsSemantic proximity Read ↗

Neuronal intermediate filaments and neurodegenerative disorders.Semantic proximity Read ↗

Abnormal Tau-Containing Filaments in Neurodegenerative DiseasesSemantic proximity Read ↗

Current concepts and molecular pathology of neurodegenerative diseasesSemantic proximity Read ↗

Much More Than a Scaffold: Cytoskeletal Proteins in Neurological Disorders.Semantic proximity Read ↗

The Neglected Genes of ALS: Cytoskeletal Dynamics Impact Synaptic Degeneration in ALSSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.