Article
Mendelian Randomization Analysis Identified Potential Genes Pleiotropically Associated with Polycystic Ovary Syndrome.
Reproductive sciences (Thousand Oaks, Calif.) - 1 Mar 2022
Sun Qian, Gao Yuan, Yang Jingyun, Lu Jiayi, Feng Wen, Yang Wen
Abstract excerpt
Polycystic ovary syndrome (PCOS) is a common endocrine disorder with unclear etiology. Some genes may be pleiotropically or potentially causally associated with PCOS. In the present study, the summary data-based Mendelian randomization (SMR) method integrating genome-wide association study (GWAS) for PCOS and expression quantitative trait loci (eQTL) data was applied to identify genes that were pleiotropically...
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