Article
The Association Between Genetically Predicted Systemic Inflammatory Regulators and Polycystic Ovary Syndrome: A Mendelian Randomization Study.
Frontiers in endocrinology - 1 Jan 2021
Chen Hanxiao, Zhang Yaoyao, Li Shangwei, Tao Yuanzhi, Gao Rui, Xu Wenming, Yang Yihong, Cheng Kemin, Wang Yan, Qin Lang
Abstract excerpt
Polycystic ovary syndrome (PCOS) is one of the most common endocrine and metabolic diseases among women of reproductive age. Inflammation may be involved in the pathogenesis of PCOS, but its exact relationship with PCOS remains unclear. Herein, we investigate the causal association between systemic inflammatory regulators and PCOS risk through a two-sample Mendelian randomization (MR) approach based on the latest...
Topics
- Adult
- Biomarkers
- Cytokines
- Female
- Finland
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Humans
- Inflammation
- Inflammation Mediators