Article
[Overlapping features of frontotemporal dementia and amyotrophic lateral sclerosis].
Revista medica de Chile - 1 Jul 2014
Lillo Patricia, Matamala José Manuel, Valenzuela Daniel, Verdugo Renato, Castillo José Luis, Ibáñez Agustín, Slachevsky Andrea
Abstract excerpt
Recent genetic and neuropathologic advances support the concept that frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are overlapping multisystem disorders. While 10-15% of ALS patients fulfil criteria for FTD, features of motor neuron disease appear in approximately 15% of FTD patients, during the evolution of the disease. This overlap has been reinforced by the discovery of Transactive...
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