Article
Tale of two diseases: amyotrophic lateral sclerosis and frontotemporal dementia.
Neurology India - 1 Jan 2000
Verma Ashok
Abstract excerpt
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) were independently described in clinical and pathological details more than a century ago. Recent breakthrough discoveries identifying common genes that are causal to either ALS or FTD or an overlapping ALS-FTD syndrome have dramatically transformed our view regarding their pathogenesis. Most recently, a massive hexanucleotide (GGGGCC) repeat...
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