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Article

From basic research to the clinic: innovative therapies for ALS and FTD in the pipeline.

Molecular neurodegeneration - 1 Jun 2020

Liscic Rajka Maria, Alberici Antonella, Cairns Nigel John, Romano Maurizio, Buratti Emanuele

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) and Frontotemporal Degeneration (FTD) are neurodegenerative disorders, related by deterioration of motor and cognitive functions and short survival. Aside from cases with an inherited pathogenic mutation, the causes of the disorders are still largely unknown and no effective treatment currently exists. It has been shown that FTD may coexist with ALS and this overlap occurs at...

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Identifiers

PMID: 32487123
DOI: 10.1186/s13024-020-00373-9
PMCID: PMC7268618

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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