DNA Methylation Profiles of Ovarian Clear Cell Carcinoma.

doi:10.1158/1055-9965.EPI-21-0677

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

DNA Methylation Profiles of Ovarian Clear Cell Carcinoma.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2022

Cunningham Julie M, Winham Stacey J, Wang Chen, Weiglt Britta, Fu Zhuxuan, Armasu Sebastian M, McCauley Bryan M, Brand Alison H, Chiew Yoke-Eng, Elishaev Esther, Gourley Charlie, Kennedy Catherine J, Laslavic Angela, Lester Jenny, Piskorz Anna, Sekowska Magdalena, Brenton James D, Churchman Michael, DeFazio Anna, Drapkin Ronny, Elias Kevin M, Huntsman David G, Karlan Beth Y, Köbel Martin, Konner Jason, Lawrenson Kate, Papaemmanuil Elli, Bolton Kelly L, Modugno Francesmary, Goode Ellen L

Abstract excerpt

BACKGROUND: Ovarian clear cell carcinoma (OCCC) is a rare ovarian cancer histotype that tends to be resistant to standard platinum-based chemotherapeutics. We sought to better understand the role of DNA methylation in clinical and biological subclassification of OCCC. METHODS: We interrogated genome-wide methylation using DNA from fresh frozen tumors from 271 cases, applied nonsmooth nonnegative matrix...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma, Clear Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aneuploidy

Share to Class I Phosphatidylinositol 3-Kinases

Share to CpG Islands

Share to DNA Methylation

Share to Neoplasm Staging

Share to Ovarian Neoplasms

Share to Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 34697060
DOI: 10.1158/1055-9965.EPI-21-0677
PMCID: PMC8755592

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA Methylation Profiles of Ovarian Clear Cell Carcinoma.PMID 34697060Read ↗

Molecular Classification of Epithelial Ovarian Cancer Based on Methylation Profiling: Evidence for Survival HeterogeneitySemantic proximity Read ↗

Integrated genomic/epigenomic analysis stratifies subtypes of clear cell ovarian carcinoma, highlighting their cellular origin.Semantic proximity Read ↗

Analysis of gene expression signatures identifies prognostic and functionally distinct ovarian clear cell carcinoma subtypes.Semantic proximity Read ↗

Review the progression of ovarian clear cell carcinoma from the perspective of genomics and epigenomicsSemantic proximity Read ↗

Comprehensive molecular characterization identifies therapeutic vulnerabilities in ovarian clear cell carcinoma.Semantic proximity Read ↗

Integrating Genomic, Epigenomic, and Transcriptomic Features Reveals Modular Signatures Underlying Poor Prognosis in Ovarian CancerSemantic proximity Read ↗

APOBEC3B stratifies ovarian clear cell carcinoma with distinct immunophenotype and prognosis.Semantic proximity Read ↗

Molecular Subclasses of Clear Cell Ovarian Carcinoma and Their Impact on Disease Behavior and Outcomes.Semantic proximity Read ↗

DNA methylation is a key determinant of response to targeted and immune checkpoint therapies in metastatic renal cell carcinomaSemantic proximity Read ↗

Genomic profiling of ovarian clear cell carcinoma in Chinese patients reveals potential prognostic biomarkers for survival.Semantic proximity Read ↗

Genomic landscape of ovarian clear cell carcinoma via whole exome sequencing.Semantic proximity Read ↗

Genomic Analysis Reveals the Molecular Heterogeneity of Ovarian Clear Cell CarcinomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.