Article
Association of single-nucleotide polymorphism 3 and c.553G>T of APOA5 with hypertriglyceridemia after treatment with highly active antiretroviral therapy containing protease inhibitors in hiv-infected individuals in Taiwan.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Mar 2009
Chang Sui-Yuan, Ko Wei-Shin, Kao Jau-Tsuen, Chang Lan-Yang, Sun Hsin-Yun, Chen Mao-Yuan, Hsieh Szu-Min, Sheng Wang-Huei, Chang Shu-Fang, Liu Wen-Chun, Wu Cheng-Hsin, Hsu Hui-Jen, Kao Chuan-Liang, Lee Chun-Nan, Hung Chien-Ching, Chang Shan-Chwen
Abstract excerpt
We investigated the relationship between hypertriglyceridemia and the single-nucleotide polymorphisms (SNPs) on APOA5 in human immunodeficiency virus (HIV)-infected patients receiving highly active antiretroviral therapy (HAART) in Taiwan. Receipt of protease inhibitor-based HAART, high baseline triglyceride levels, and carriage of APOA5 SNP3 or c.553G>T variants or APOA5 SNP1T/SNP2G/SNP3C/c.553T haplotype were...
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