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Angiotensin II-Induced Long Non-Coding RNA Alivec Regulates Chondrogenesis in Vascular Smooth Muscle Cells.

Cells - 9 Oct 2021

Samara Vishnu Amaram, Das Sadhan, Reddy Marpadga A, Tanwar Vinay Singh, Stapleton Kenneth, Leung Amy, Abdollahi Maryam, Ganguly Rituparna, Lanting Linda, Natarajan Rama

Abstract excerpt

Long non-coding RNAs (lncRNAs) play key roles in Angiotensin II (AngII) signaling but their role in chondrogenic transformation of vascular smooth muscle cells (VSMCs) is unknown. We describe a novel AngII-induced lncRNA Alivec (Angiotensin II-induced lncRNA in VSMCs eliciting chondrogenic phenotype) implicated in VSMC chondrogenesis. In rat VSMCs, Alivec and the nearby gene Acan, a chondrogenic marker, were...

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PMID: 34685676
DOI: 10.3390/cells10102696
PMCID: PMC8535098

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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