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Article

Apocynin attenuates angiotensin II-induced vascular smooth muscle cells osteogenic switching via suppressing extracellular signal-regulated kinase 1/2.

Oncotarget - 13 Dec 2016

Feng Weijing, Zhang Kun, Liu Yu, Chen Jie, Cai Qingqing, Zhang Yinyin, Wang Mongheng, Wang Jingfeng, Huang Hui

Abstract excerpt

Vascular calcification (VC) is a significant risk factor for cardiovascular morbidity and mortality. We recently reported that apocynin had benefits for preventing cardiovascular diseases. However, whether apocynin could attenuate VC is unknown. Here, we investigated the role of apocynin in VC and its underlying mechanisms. 163 participants with high or normal ankle-brachial index (ABI) were enrolled in this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Muscle, Smooth, Vascular

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Source

Open in PubMed Open full text

Identifiers

PMID: 27835878
DOI: 10.18632/oncotarget.13193
PMCID: PMC5347790

Genes

BMP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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