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Article

MicroRNAs in the Onset of Schizophrenia.

Cells - 6 Oct 2021

Thomas Kristen T, Zakharenko Stanislav S

Abstract excerpt

Mounting evidence implicates microRNAs (miRNAs) in the pathology of schizophrenia. These small noncoding RNAs bind to mRNAs containing complementary sequences and promote their degradation and/or inhibit protein synthesis. A single miRNA may have hundreds of targets, and miRNA targets are overrepresented among schizophrenia-risk genes. Although schizophrenia is a neurodevelopmental disorder, symptoms usually do...

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PMID: 34685659
DOI: 10.3390/cells10102679
PMCID: PMC8534348

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