Article
Association of microRNA137 gene polymorphisms with age at onset and positive symptoms of schizophrenia in a Han Chinese population.
International journal of psychiatry in medicine - 1 Jan 2014
Wang Shuai, Li Wenqiang, Zhang Hongxing, Wang Xiujuan, Yang Ge, Zhao Jingyuan, Yang Yongfeng, Lv Luxian
Abstract excerpt
OBJECTIVES: MicroRNA137 (miRNA137) regulates several gene expressions involved in brain development, and a recent large genome wide association study (GWAS) revealed a possible association between miRNA137 and schizophrenia. METHODS: The allelic variants of rs66642155, a variable number tandem repeat polymorphism, and the single nucleotide polymorphism rs1625579 A/C in the miRNA137 host gene fragment were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
