Article
Formalin-Fixed and Paraffin-Embedded Samples for Next Generation Sequencing: Problems and Solutions.
Genes - 23 Sept 2021
Cazzato Gerardo, Caporusso Concetta, Arezzo Francesca, Cimmino Antonietta, Colagrande Anna, Loizzi Vera, Cormio Gennaro, Lettini Teresa, Maiorano Eugenio, Scarcella Vincenza Sara, Tarantino Paola, Marrone Maricla, Stellacci Alessandra, Parente Paola, Romita Paolo, De Marco Aurora, Venerito Vincenzo, Foti Caterina, Ingravallo Giuseppe, Rossi Roberta, Resta Leonardo
Abstract excerpt
Over the years, increasing information has been asked of the pathologist: we have moved from a purely morphological diagnosis to biomolecular and genetic studies, which have made it possible to implement the use of molecular targeted therapies, such as anti-epidermal growth factor receptor (EGFR) molecules in EGFR-mutated lung cancer, for example. Today, next generation sequencing (NGS) has changed the approach...
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