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Article

Neuroendocrine Differentiation in Conventional Colorectal Adenocarcinomas: Incidental Finding or Prognostic Biomarker?

12 Oct 2021

Abstract excerpt

Background: Colorectal mixed adenoneuroendocrine carcinomas (MANECs) are clinically highly aggressive neoplasms. MANECs are composed of variable adenocarcinoma components combined with morphologically distinct neuroendocrine carcinoma components, which are confirmed by synaptophysin immunohistochemistry, the gold standard marker of a neuroendocrine differentiation. However, the biological behavior of...

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Neuroblastoma Research and Treatments
Neuroendocrine Tumor Research Advances
Neuropeptides and Animal Physiology

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34680258
DOI: 10.3390/cancers13205111

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