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Article

Association between genetic variants of the cholinergic system and postoperative delirium and cognitive dysfunction in elderly patients.

BMC medical genomics - 21 Oct 2021

Heinrich Maria, Sieg Miriam, Kruppa Jochen, Nürnberg Peter, Schreier Peter H, Heilmann-Heimbach Stefanie, Hoffmann Per, Nöthen Markus M, Janke Jürgen, Pischon Tobias, Slooter Arjen J C, Winterer Georg, Spies Claudia D

Abstract excerpt

BACKGROUND: Postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) are frequent and serious complications after surgery. We aim to investigate the association between genetic variants in cholinergic candidate genes according to the Kyoto encyclopedia of genes and genomes - pathway: cholinergic neurotransmission with the development of POD or POCD in elderly patients. METHODS: This analysis is...

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Identifiers

PMID: 34674705
DOI: 10.1186/s12920-021-01071-1
PMCID: PMC8529799

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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