Article
[Genetic basis of postoperative cognitive dysfunction].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova - 1 Jan 2024
Saltanova V A, Kicherova O A, Reikhert L I, Doyan Yu I, Mazurov N A
Abstract excerpt
This review highlights literature data on potential genetic markers that potentially influence the development of postoperative cognitive dysfunction, such as TOMM40, APOE, TREM2, METTL3, PGC1a, HMGB1 and ERMN. The main pathogenetic mechanisms triggered by these genes and leading to the development of cognitive impairment after anesthesia are described. The paper systematizes previously published works that...
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