Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Robust estimates of heritable coronary disease risk in individuals with type 2 diabetes.

Genetic epidemiology - 1 Feb 2022

Grace Christopher, Hopewell Jemma C, Watkins Hugh, Farrall Martin, Goel Anuj

Abstract excerpt

Type 2 diabetes (T2D) is an important heritable risk factor for coronary artery disease (CAD), the risk of both diseases being increased by metabolic syndrome (MS). With the availability of large-scale genome-wide association data, we aimed to elucidate the genetic burden of CAD risk in T2D predisposed individuals within the context of MS and their shared genetic architecture. Mendelian randomization (MR)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bayes Theorem
Share to Coronary Artery Disease
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 34672391
DOI: 10.1002/gepi.22434
PMCID: PMC8983061

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Robust estimates of heritable coronary disease risk in individuals with type 2 diabetes.PMID 34672391Read ↗

Shared Genetic Contribution of Type 2 Diabetes and Cardiovascular Disease: Implications for Prognosis and Treatment.Semantic proximity Read ↗

Type 2 diabetes mellitus and cardiovascular health: Evidence of causal relationships in a European ancestry population.Semantic proximity Read ↗

Genetics Insights in the Relationship Between Type 2 Diabetes and Coronary Heart Disease.Semantic proximity Read ↗

Polygenic risk for coronary heart disease acts through atherosclerosis in type 2 diabetes.Semantic proximity Read ↗

Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complicationsSemantic proximity Read ↗

Genetic Predisposition to Coronary Artery Disease in Type 2 Diabetes Mellitus.Semantic proximity Read ↗

A precision medicine approach to coronary artery disease risk prediction and mitigation in people with type 2 diabetesSemantic proximity Read ↗

Integrative genetic analysis reveals shared genetic architecture underlying coronary artery disease, CT-Defined coronary atherosclerosis, and cardiometabolic risk factors.Semantic proximity Read ↗

Exploring the Genetic Relationship Between Type 2 Diabetes and Cardiovascular Disease: A Large-Scale Genetic Association and Polygenic Risk Score Study.Semantic proximity Read ↗

Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.Semantic proximity Read ↗

Identification of shared genetic susceptibility locus for coronary artery disease, type 2 diabetes and obesity: a meta-analysis of genome-wide studies.Semantic proximity Read ↗

Genetic Insight into the Paradoxical Relationship among Diabetes, Coronary Artery Disease, and Abdominal Aortic AneurysmSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.