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Article

Association of Estrogen Receptor Genes Polymorphisms With Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis Based on Observational Studies.

Frontiers in endocrinology - 1 Jan 2021

Zhou Siyu, Wen Shu, Sheng Yongcheng, Yang Meina, Shen Xiaoyang, Chen Yan, Kang Deying, Xu Liangzhi

Abstract excerpt

Purpose: Controversial results existed in amounts of studies investigating the authentic association of estrogen receptor genes (ESR1 and ESR2) polymorphisms with the occurrence and progression of polycystic ovary syndrome (PCOS). The inconsistency might result from different loci, sample sizes, and ethnicities. To find the potential correlations between ESR1/ESR2 polymorphisms and PCOS risk, we conducted the...

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Identifiers

PMID: 34671317
DOI: 10.3389/fendo.2021.726184
PMCID: PMC8521002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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