Biochemical Characterization and Molecular Determination of Estrogen Receptor-α (ESR1 PvuII-rs2234693 T>C) and MiRNA-146a (rs2910164 C>G) Polymorphic Gene Variations and Their Association with the Risk of Polycystic Ovary Syndrome

doi:10.3390/ijerph19053114

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Biochemical Characterization and Molecular Determination of Estrogen Receptor-α (ESR1 PvuII-rs2234693 T>C) and MiRNA-146a (rs2910164 C>G) Polymorphic Gene Variations and Their Association with the Risk of Polycystic Ovary Syndrome

International journal of environmental research and public health - 6 Mar 2022

Mir Rashid, Tayeb Faris J, Barnawi Jameel, Jalal Mohammed M, Saeedi Nizar H, Hamadi Abdullah, Altayar Malik A, Alshammari Sanad E, Mtiraoui Nabil, Ali Mohammed Eltigani, Duhier Faisel M Abu, Ullah Mohammad Fahad

Abstract excerpt

Polycystic ovary syndrome (PCOS) is regarded as one of the most frequently encountered endocrine disorders and affects millions of young women worldwide, resulting in an array of complex metabolic alterations and reproductive failure. PCOS is a risk factor for diabetes mellitus, obstructive sleep apnea, obesity and depression in patients. Estrogen receptors (ESRs) are significant candidates in endocrine function...

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PMID: 35270805
DOI: 10.3390/ijerph19053114
PMCID: PMC8910123

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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