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Article

Effect of ESR1 and ESR2 polymorphisms on ovarian response in assisted reproductive technology cycles: a systematic review and meta-analysis.

Scientific reports - 5 Jun 2026

Fathima Khan Zahara, R Vani Lakshmi, Irungu Stella, Gupta Aditi, Dhyani Vijay Shree, Adiga Prashanth, Mukherjee Srabani, Adiga Satish Kumar, Uppangala Shubhashree

Abstract excerpt

Genetic factors contribute to poor ovarian response (POR) in assisted reproductive technology cycles, with estrogen receptor gene polymorphisms (ESR1 and ESR2) being explored as a causative factor in many studies. However, there is no systematic review and meta-analysis conducted on these studies to assess the association of these receptor polymorphisms on POR. This systematic review and meta-analysis evaluated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42248903
DOI: 10.1038/s41598-026-53350-5
PMCID: PMC13482574

Genes

ESR1
ESR2
POR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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