Association of Polymorphisms in FSHR, ESR1, and BMP15 with Primary Ovarian Insufficiency and Meta-Analysis

Abstract excerpt

Primary ovarian insufficiency (POI) can lead to menstrual disturbance, resulting in ovarian dysfunction before age 40. Prevalence of POI is usually less than 1%; however, ethnicity or population characteristics may affect prevalence. POI is a heterogeneous disease that results from abnormalities in immunological and hormonal factors. Genetic factors can also contribute to POI. Here, we examine FSHR, ESR1, and...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Ovarian function and disorders
• Share to Reproductive Biology and Fertility
• Share to Reproductive System and Pregnancy