Article
Use of the PsycheMERGE Network to Investigate the Association Between Depression Polygenic Scores and White Blood Cell Count.
JAMA psychiatry - 1 Dec 2021
Sealock Julia M, Lee Younga H, Moscati Arden, Venkatesh Sanan, Voloudakis Georgios, Straub Peter, Singh Kritika, Feng Yen-Chen A, Ge Tian, Roussos Panos, Smoller Jordan W, Chen Guanhua, Davis Lea K
Abstract excerpt
Importance: Although depression is a common psychiatric disorder, its underlying biological basis remains poorly understood. Pairing depression polygenic scores with the results of clinical laboratory tests can reveal biological processes involved in depression etiology and in the physiological changes resulting from depression. Objective: To characterize the association between depression polygenic scores and an...
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