Article

SARS-CoV-2 Infected Cardiomyocytes Recruit Monocytes by Secreting CCL2

2020-11-17

Abstract excerpt

<title>Abstract</title> <p>Heart injury has been reported in up to 20% of COVID-19 patients, yet the cause of myocardial histopathology remains unknown. In order to study the cause of myocardial pathology in COVID-19 patients, we used a hamster model to determine whether following infection SARS-CoV-2, the causative agent of COVID-19, can be detected in heart tissues. Here, we clearly demonstrate that viral RNA a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ff5da952-0176-5572-b251-7e398852f274
DOI: 10.21203/rs.3.rs-94634/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

SARS-CoV-2 Infected Cardiomyocytes Recruit Monocytes by Secreting CCL2DOI 10.21203/rs.3.rs-94634/v1Read

Necroptosis Drives Major Adverse Cardiovascular Events During Severe COVID-19Semantic proximity Read

Cardiac SARS-CoV-2 infection is associated with distinct transcriptomic changes within the heartSemantic proximity Read

Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Platform to Study SARS-CoV-2 Related Myocardial InjurySemantic proximity Read

Cardiac SARS-CoV-2 infection is associated with pro-inflammatory transcriptomic alterations within the heartSemantic proximity Read

Evidence of SARS-CoV-2 transcriptional activity in cardiomyocytes of COVID-19 patients without clinical signs of cardiac involvementSemantic proximity Read

Innate Immune Activation and Mitochondrial ROS Invoke Persistent Cardiac Conduction System Dysfunction after COVID-19Semantic proximity Read

SARS-CoV-2 infection of human iPSC-derived cardiac cells predicts novel cytopathic features in hearts of COVID-19 patientsSemantic proximity Read

SARS-CoV-2 infects and induces cytotoxic effects in human cardiomyocytesSemantic proximity Read

Molecular mechanisms of Cardiac Injury associated with myocardial SARS-CoV-2 infectionSemantic proximity Read

Human iPSC-Derived Cardiomyocytes Are Susceptible to SARS-CoV-2 InfectionSemantic proximity Read

SARS-CoV-2 Infects Human Pluripotent Stem Cell-Derived Cardiomyocytes, Impairing Electrical and Mechanical FunctionSemantic proximity Read

Landscape of molecular crosstalk between SARS-CoV-2 infection and cardiovascular diseases: emphasis on mitochondrial dysfunction and immune-inflammationSemantic proximity Read