Article

Human cardiac stromal cells exposed to SARS-CoV-2 evolve into hyper-inflammatory/<i>pro</i>-fibrotic phenotype and produce infective viral particles depending on the levels of ACE2 receptor expression

2020-11-10

Abstract excerpt

Patients with severe respiratory syndrome caused by SARS-CoV-2 undergo cardiac complications due to hyper-inflammatory conditions. Although the presence of the virus has been detected in the myocardium of infected patients, and infection of cardiac cells may involve ACE2 receptor, the underlying molecular/cellular mechanisms are still uncharacterized. We analyzed expression of ACE2 receptor in primary human cardia...

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Literature Corpus work: 5c1d74a7-ab0f-5f2a-a00c-b1adfc8a1bdc
DOI: 10.1101/2020.11.06.20226423

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