Article
Pleiotropic Effects of Functional MUC1 Variants on Cardiometabolic, Renal, and Hematological Traits in the Taiwanese Population.
International journal of molecular sciences - 30 Sept 2021
Teng Ming-Sheng, Wu Semon, Hsu Lung-An, Chou Hsin-Hua, Ko Yu-Lin
Abstract excerpt
MUC1 is a transmembrane mucin involved in carcinogenesis and cell signaling. Functional MUC1 variants are associated with multiple metabolic and biochemical traits. This study investigated the association of functional MUC1 variants with MUC1 DNA methylation and various metabolic, biochemical, and hematological parameters. In total, 80,728 participants from the Taiwan Biobank were enrolled for association...
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