Article
Effect of Tumor Microenvironment and Angiogenesis on Clinical Outcomes of Primary Central Nervous System Lymphoma.
BioMed research international - 1 Jan 2021
Wang Hui-Ching, Hsiao Hui-Hua, Du Jeng-Shiun, Cho Shih-Feng, Yeh Tsung-Jang, Gau Yuh-Ching, Liu Yi-Chang, Moi Sin-Hua
Abstract excerpt
Primary central nervous system lymphoma (PCNSL) is a rare lymphoma, and the disease course is often aggressive with poor prognosis outcomes. PCNSL undergoes germinal center reactions and impairs B-cell maturation. However, angiogenesis is also involved in the tumorigenesis and progression of PCNSL. This study investigated the effects of the tumor microenvironment and angiogenesis-associated genomic alterations on...
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