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Article

Genetic variants in RNA m5 C modification genes associated with survival and chemotherapy efficacy of colorectal cancer.

Cancer medicine - 1 Jan 2023

Chen Silu, Cao Xiangming, Ben Shuai, Zhu Lingjun, Gu Dongying, Wu Yuan, Li Shuwei, Yu Qiang

Abstract excerpt

BACKGROUND: Colorectal cancer is one of the most common malignant digestive tract tumors with a poor prognosis. RNA 5-methylcytosine (m5 C) is an important posttranscriptional widespread modification involved in many biological processes. However, the association between genetic variations of m5 C modification genes and the prognostic value of colorectal cancer remains unclear. METHODS: We investigated the...

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PMID: 35861369
DOI: 10.1002/cam4.5018
PMCID: PMC9883553

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